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Senior Research Associate

Company: RootStaff
Location: San Rafael
Posted on: June 19, 2022

Job Description:

Title: Senior Research Associate IILocation: San Rafael, CA 94903Duration: 12 Months Assignment

  • Industry lab exp preferred
  • 100% lab onsite role
  • Differentiating cells in cardiomyocytes and working knowledge of Cardiac fibroblast, Cardiac fibrosis, Genetic inherited cardiac diseases OR
  • At least strong cell/molecular biology exp in any background other than cardiac with fresh MS or PhD
  • Initial with 1 then panel interview Job DescriptionDuties
  • The Cardiovascular Cell Biology group at Client is seeking a SRA2 with experience in modeling cardiovascular disease using a broad range of in vitro models, particularly in the context of evaluating novel therapeutic approaches using gene-edited or patient-derived iPSC lines.
  • This position provides ample opportunities to be part of highly impactful Teams, with opportunities for career growth in a friendly, collaborative, and passionate research environment.
  • He/She is a highly motivated and driven cell biologist with experience in iPS cardiomyocyte differentiation, who develops approaches to model human cardiovascular disease "in a dish" for new and existing internal cardiac projects.
  • The successful candidate will often take on the Cell Biology Functional Lead role in Team-based projects and therefore must be able to work collaboratively.
  • The successful candidate will be a proactive self-starter, with clear passion to progress Her/His in vitro technical scientific skills, generate highly impactful data, and an ability to thrive in a fast-paced colloborative team environment.
  • He/She will communicate scientific findings at Team Meetings, as well as at several forums throughout the company.
  • She/He will partner closely with research associates, senior research associates and scientists within the cardiovascular research group, and other functional groups within Research to support the discovery and pre-clinical development of a wide-range of therapeutic modalities. This is a full-time lab-based position.Responsibilities
    • Takes on a leadership role to bring in new technical skills, leads the development, evaluation, and implementation of state-of-the-art cell-based disease models to identify novel therapeutic interventions.
    • This exploratory cell biology work will contribute to our understanding of the mechanisms of cardiac disease pathogenesis, and will also provide preclinical proof-of-concept data to guide in the development of novel and safe therapeutics for inherited cardiac diseases with unmet need.
    • Work as the in vitro Team lead in the development of a novel therapeutic for an inherited cardiac disease.
    • Perform cell biology work, publish findings in high-impact journals and present research at major conferences.
    • Effectively partner with the program team, other SRAs and scientists to develop and execute on the program's strategic plan.
    • Present program data at a range of internal forums, including Research Seminars.
    • Work closely as part of a highly focused and passionate team of in vitro cardiovascular scientists
    • Lead or contribute to study synopses, protocols, study reports and publications arising from Team projects.Skills
      • Experience with expanding, differentiating and characterizing gene-edited or patient iPSC-derived cardiomyocytes, and modeling human cardiovascular disease "in a dish" is preferable.
      • Excellent working cell biology experience in at least one of the following: functional cardiomyocyte assays, experience with culturing iPS-derived cardiomyocytes, isolation and maintenance of primary cardiac cells, monitoring cardiac cell function with cardio xCELLigence or by high speed calicum imaging, confocal microscopy, force traction microscopy, high content microscopy, live cell imaging, DNA editing.
      • Excellent written and verbal communication skills. Education
        • Required: A Master's degree with strong experience in cardiovascular research and cardiovascular physiology, pharmacology or a related subject area.Education & Experience Level
          • MS with 1+ year of industry experience; BS with 5+ years. Very strong technical and analytical skills. Must be a team player.

Keywords: RootStaff, San Rafael , Senior Research Associate, Other , San Rafael, California

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