Team Lead - Senior Scientist
Location: San Rafael
Posted on: November 22, 2022
Koniku is an early-stage, rapidly-growing company based in
Silicon Valley. We build smell cyborgs by merging genetically
modified living biological neurons with classic devices. Our
flagship device, the Konikore---, detects smells using GPCR's or
olfactory receptor proteins hosted in biological cells. There are
dynamic applications in healthcare, security, synthetic flavors &
foods, and much more. We partner with a range of Fortune 500
companies as Technology Integrators and have been recently featured
by The Financial Times, CNN, Bloomberg, TechCrunch & others.
Notable partners, customers and investors include: Airbus, BASF,
Thermo Fisher Scientific, Fraunhofer Institute Stuttgart, P&G,
SoftBank, Platform Capital, IndieBio (SOSv). Beyond the numerous
B2B opportunities, we aim to have a Konikore in ten million homes
as a real-time disease diagnostic tool within the next decade.
Koniku is a face-to-face company and our campus & culture are the
nucleus of the Koniku spirit. Our headquarters include a
next-generation deep technology Wetlab and a robust manufacturing
facility, alongside our corporate, administrative & customer
support teams. We are driven by a fundamental belief that "Bio is
Tech---".Job Summary This role is suitable for individuals with
deep knowledge and a demonstrable track record doing in vitro
neuroscience, mammalian cell biology & cellular signaling. Your
role will involve developing new neural cell-based assays and
optimizing existing ones. This role is not for "research-focused
candidates". We are interested in "how to" as opposed to "why". We
seek a technology developer within a technology & products team.You
will work with the team to develop an array of neural cell
libraries. Work on at the forefront of expression systems/methods
for olfactory receptors. Your work may include introducing further
exogenous genes into neural cells to achieve specific
("non-physiological") functions. We expect you to design and
implement state-of-the-art expression vectors/systems for the
precise and controllable behavior of neural cells and olfactory
receptors. This role is one of the multiple roles being actively
recruited. The ideal candidate thrives by leading with clearly
communicated updates, timelines, and solid statistically relevant
data. Why It MattersKoniku's wetware technology relies heavily on
the biological side. We believe in moving most of the processing
work our chips do to the biological side. That means if there is a
detection, processing or computational problem to be solved, can we
use biology to solve it first? The biological part of our chips,
neural cells expressing olfactory receptors - GPCRs should do as
much work as possible before passing the resulting signals to the
electronics.We are working to make the biology aspects more robust,
faster, and more sensitive. The role is a key contributor and team
leader for this technology vision. The recruited individual is a
key thought leader, technology driver and a primary decision-maker
on the direction of Koniku's synthetic neurobiology. Importantly,
the role needs an individual with leadership traits, a strong bias
to execute and deliver results that meet Koniku's goals and
- Lead the design and perform hands-on work designing,
implementing and testing/screening genetic constructs in neural
- Design and implement synthetic pathways to achieve specific
performance features, such as faster signaling, increased
signal-to-noise, shortened refractory period, and other
- Rigorously analyze, interpret and deliver results in a timely
fashion to meet the company's objectives.
- Lead a small team of junior scientists in solving challenging
synthetic problems from a fresh perspective.
- Conduct comprehensive literature analysis with an emphasis on
pursuing great reproducible science.
- Immaculate records of experiments in physical and online lab
- A Ph.D in synthetic biology, neuroscience or olfaction,
bioengineering, genetics, biochemistry, or related fields is a must
- Experience in cellular signaling, protein expression strategies
and related disciplines is a strong plus.
- At least five years experience in neural cells engineering from
a reputable lab or company is highly desirable. Similar experience
in mammalian cell engineering will be considered.
- Demonstrable experience and solid results in using
computational biology to rationally design signaling pathways is a
- Familiarity with a programming language like R, Python, or
similar programming language is a plus.
- The ideal candidate is keen to see their work in the real
world, has a deep desire to automate and transmit their results
readily to other teams for scale. You are able to own your work,
pass it on and move to newer challenging projects.
- This role is suitable for an individual with prior industrial
or start up experience. Alternatively, a focused and dedicated
individual with entrepreneurial drive and deep scientific passion
would find this position meaningful.
- You are a strong leader and great team player.
Keywords: Koniku, San Rafael , Team Lead - Senior Scientist, Other , San Rafael, California
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