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Senior Research Associate

Company: Tucker Parker Smith Group (TPS Group)
Location: San Rafael
Posted on: January 20, 2023

Job Description:

Senior Research Associate
Location: San Rafael, CA

Direct Hire

Salary: $80,000-115,000/year



Our leading pharmaceutical client is seeking a Senior Research Associate to work directly with scientists in the Molecular Medicine team to develop and implement Client assays to contribute to scientific investigation in clinical and preclinical studies.



Duties:


  • Design and execute experiments to understand molecular and cellular mechanisms underlying rAAV gene therapy efficacy, variability, and durability
  • Develop and perform a variety of analytical methods to detect nucleic acids, biomarkers, and drug in biological matrices to support pre-clinical and clinical programs
  • Techniques may include nucleic acid extraction and quantitation, single cell sequencing, qPCR, multi-color ddPCR
  • Optimize, troubleshoot, and perform nuclei isolation from animal tissues followed by sequencing
  • Present results, conclusions, and implications to MolecularMedicine, BioAnalytical Sciences, and Translational Sciences groups and cross-functionally
  • Participate in external scientific meetings and contribute to original peer-reviewed publications




    Education & Experience:


    • Bachelor's degree in molecular biology, biochemistry, or a related scientific field and at least 4+ years of relevant experience or Master's degree with a least 2+ years of relevant experience
    • Experience in molecular biology techniques including DNA/RNA extractions and quantitation, reverse transcription, qPCR, ddPCR, and next generation sequencing
    • Experience in method development for single cell RNA sequencing from animal tissues
    • Demonstrated experience initiating new methods or technologies in an experimental laboratory setting
    • Familiar with single cell platforms (ie. Droplet-based or nano well technologies)
    • Basic knowledge on next generation sequencing analysis.


      Please submit your resume in Word or PDF format to be considered.

Keywords: Tucker Parker Smith Group (TPS Group), San Rafael , Senior Research Associate, Other , San Rafael, California

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