Senior Commercial Strategy Manager
Company: SmithRx
Location: San Francisco
Posted on: February 20, 2026
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Job Description:
Job Description Job Description Who We Are: SmithRx is a rapidly
growing, venture-backed Health-Tech company. Our mission is to
disrupt the expensive and inefficient Pharmacy Benefit Management
(PBM) sector by building a next-generation drug acquisition
platform driven by cutting edge technology, innovative cost saving
tools, and best-in-class customer service. With hundreds of
thousands of members onboarded since 2016, SmithRx has a solution
that is resonating with clients all across the country. We pride
ourselves for our mission-driven and collaborative culture that
inspires our employees to do their best work. We believe that the
U.S healthcare system is in need of transformation, and we come to
work each day dedicated to making that change a reality. At our
core, we are guided by our company values: Integrity: Our purpose
guides our actions and gives us confidence in the path ahead. With
unwavering honesty and dependability, we embrace the pressure of
challenging the old and exemplify ethical leadership to create the
new. Courage: We face continuous challenges with grit and
resilience. We embrace the discomfort of the unknown by balancing
autonomy with empathy, and ownership with vulnerability. We boldly
challenge the status quo to keep moving forward—always. Together:
The success of SmithRx reflects the strength of our partnerships
and the commitment of our team. Our shared values bind us together
and make us one. When one falls, we all fall; when one rises, we
all rise. Job Summary: SmithRx is seeking a Senior Commercial
Strategy Manager to join our growing team. In this strategic
leadership role, you'll collaborate directly with senior executives
and our key clients to ensure that SmithRx is achieving our
objective of providing the lowest possible drug costs. This
individual will be responsible for driving forward a range of
commercialization initiatives in helping lead SmithRx to the next
level of growth. This will entail collaborating with Sales,
Clinical Strategy, Account Management, Pricing & Proposals, Data
Analytics, and Marketing. The ideal candidate will have a strong
background in analytics, strategy, leading cross-functional
projects, business case creation, and operational execution. They
should possess a balance in connecting between analytical detail,
conceptual frameworks, and communication of results and be
comfortable charting strategy and driving execution through
ambiguous situations. What you will do: Go-To-Market Strategy
Collaborate to develop and refine new business strategies,
including new GTM channels, positioning updates, and value
proposition development Develop business case and recommendations
for new business initiatives Support customer segmentation and
segmentation/account specific planning Maintain a pulse on trends
specific to PBM as well as across the broader healthcare industry
Work closely with supply chain for deeper insight on pricing trends
and changes Build for the Future Work closely with Sales and
Proposals teams to craft offers to pharmacy consultants, brokers,
and clients which properly reflect SmithRx's value. Work with
SmithRx senior leadership to innovate and evolve performance models
for SmithRx, and the PBM industry as a whole. Engage pharmacy
consultants and brokers to educate the market about SmithRx's core
business pillars and why it optimizes client outcomes. Various
other ad hoc strategic projects aimed supporting SmithRx growth
initiatives Customer Performance & Accountability Lead Performance
Assessment initiative, in collaboration with the Account Management
and Data teams to ensure that SmithRx performance analysis is
completed and value is communicated to clients on an ongoing basis
so that our customers are aware of our value. Build a "performance
assessment playbook" to ensure SmithRx is ahead of all contract
performance accountability processes with clients and partners, and
clients are satisfied with our outcomes. Work with the Data
Analytics team to deeply understand our performance for clients,
and build reports to maximally automate the process of performance
accountability. Actively participate in deal assessment for ongoing
retention activity What you will bring to SmithRx: 8 years of
experience in analytical, financial, or strategy roles, including 3
years experience in healthcare and/or pharmacy industry related
roles. Prior experience in finance, consulting, or startup
experience, is a strong plus. Bachelor's degree or equivalent
experience, advanced degree or MBA preferred. Excel at both written
and oral communication, adeptly presenting SmithRx value
proposition and philosophy on value and accountability to audiences
including internal leaders, brokers, pharmacy consultants, and
employers. What SmithRx Offers You: Highly competitive wellness
benefits including Medical, Pharmacy, Dental, Vision, and Life
Insurance and AD&D Insurance Flexible Spending Benefits 401(k)
Retirement Savings Program Short-term and long-term disability
Discretionary Paid Time Off Paid Company Holidays Wellness Benefits
Commuter Benefits Paid Parental Leave benefits Employee Assistance
Program (EAP) Well-stocked kitchen in office locations Professional
development and training opportunities
Keywords: SmithRx, San Rafael , Senior Commercial Strategy Manager, Sales , San Francisco, California